Bone marrow microenvironment

ID2 Suppresses Multiple Myeloma Cell Proliferation by Repressing the Activity of the Transcription Factor TCF3

Fulciniti M, Yao Y, Perini T, …, Szalat R, …, Munshi NC

Blood Cancer Discovery7(1):129-141DOI: ID2 Suppresses Multiple Myeloma Cell Proliferation by Repressing the Activity of the Transcription Factor TCF3PubMed: ID2 Suppresses Multiple Myeloma Cell Proliferation by Repressing the Activity of the Transcription Factor TCF3

Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes

Binder M, Szalat RE, Talluri S, Fulciniti M, Avet-Loiseau H, Parmigiani G, Samur MK, Munshi NC

Nature Communications15(1)DOI: Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changesPubMed: Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes

Single-Cell Profiling in Multiple Myeloma: Insights, Problems, and Promises

Samur MK, Szalat R, Munshi NC

BloodDOI: Single-Cell Profiling in Multiple Myeloma: Insights, Problems, and PromisesPubMed: Single-Cell Profiling in Multiple Myeloma: Insights, Problems, and Promises

Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma

Fulciniti M, Martinez-Lopez J, Senapedis W, …, Szalat R, …, Munshi NC

Blood129(16):2233-2245DOI: Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myelomaPubMed: Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma

A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

Jakubikova J, Cholujova D, Hideshima T, …, Szalat RE, …, Anderson KC

Oncotarget7(47):77326-77341DOI: A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applicationsPubMed: A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

Bone marrow plasma cells and immune microenvironment transcriptomic architecture in AL amyloidosis during daratumumab based therapy

Szalat R, Talluri S, Wong S, Morgan G, Sanchorawala V, Munshi N, et al.

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS31:S176-S176

Composition and Dynamic Evolution of the Bone Marrow Microenvironment in AL Amyloidosis during Daratumumab Based Therapy

Szalat RE, Talluri S, Royer CM, Wong S, Morgan G, Sanchorawala V, Samur MK, Munshi NC

Blood142(Supplement 1):3416-3416DOI: Composition and Dynamic Evolution of the Bone Marrow Microenvironment in AL Amyloidosis during Daratumumab Based Therapy

OAB-021: High-risk multiple myeloma due to extramedullary disease-like gene expression induced by bone marrow stromal cells

Binder M, Szalat R, Fulciniti M, Avet-Loiseau H, Parmigiani G, Samur M, Munshi N

Clinical Lymphoma Myeloma and Leukemia22:S13DOI: OAB-021: High-risk multiple myeloma due to extramedullary disease-like gene expression induced by bone marrow stromal cells

Chromatin Remodeling and Associated Changes in Gene Expression Induced By Bone Marrow Stromal Cells Identify Features of High-Risk Multiple Myeloma

Binder M, Szalat RE, Fulciniti M, Parmigiani G, Samur MK, Munshi NC

Blood138(Supplement 1):2672-2672DOI: Chromatin Remodeling and Associated Changes in Gene Expression Induced By Bone Marrow Stromal Cells Identify Features of High-Risk Multiple Myeloma

Bone marrow microenvironment induces genomic instability and enables clonal evolution in multiple myeloma

Perini T, Szalat R, Fulciniti M, Samur MK, Lopez MA, Nanjappa P, Wen K, et al.

Blood130:4408