Genomics and omics

Epigenomics and chromatin

4 papers and 7 abstracts co-authored by Raphael E. Szalat. Current lab members are shown in bold.

Papers 4

  1. 2024

    Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes

    Binder M, Szalat RE, Talluri S, Fulciniti M, Avet-Loiseau H, Parmigiani G, Samur MK, Munshi NC

    Nature Communications15(1)DOI: Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changesPubMed: Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes

  2. 2019

    Functional profiling of nucleotide Excision repair in breast cancer

    Rajkumar-Calkins AS, Szalat R, Dreze M, …, Mouw KW

    DNA Repair82:102697DOI: Functional profiling of nucleotide Excision repair in breast cancerPubMed: Functional profiling of nucleotide Excision repair in breast cancer

  3. 2018

    Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

    Fulciniti M, Lin CY, Samur MK, …, Szalat RE, …, Munshi NC

    Cell Reports25(13):3693-3705.e6DOI: Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple MyelomaPubMed: Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

  4. 2015

    Genomic heterogeneity in multiple myeloma

    Szalat R, Munshi NC

    Current Opinion in Genetics & Development30:56-65DOI: Genomic heterogeneity in multiple myelomaPubMed: Genomic heterogeneity in multiple myeloma

Abstracts & posters 7

  1. 2021

    Chromatin Remodeling and Associated Changes in Gene Expression Induced By Bone Marrow Stromal Cells Identify Features of High-Risk Multiple Myeloma

    Binder M, Szalat RE, Fulciniti M, Parmigiani G, Samur MK, Munshi NC

    Blood138(Supplement 1):2672-2672DOI: Chromatin Remodeling and Associated Changes in Gene Expression Induced By Bone Marrow Stromal Cells Identify Features of High-Risk Multiple Myeloma

  2. 2019

    Genome wide chromatin accessibility profiling identifies chromatin signatures and novel transcription factor dependencies in multiple myeloma

    Szalat R, Lawlor M, Fulciniti M, …, Munshi N

    Clinical Lymphoma Myeloma and Leukemia19(10):e8-e9DOI: Genome wide chromatin accessibility profiling identifies chromatin signatures and novel transcription factor dependencies in multiple myeloma

  3. 2019

    Recurrent somatic Alterations in the Non-Coding Genome Alter Gene Expression Levels and Correlate With Clinical Outcome

    Samur M, Samur A, Szalat R, …, Munshi N

    Clinical Lymphoma Myeloma and Leukemia19(10):e12-e13DOI: Recurrent somatic Alterations in the Non-Coding Genome Alter Gene Expression Levels and Correlate With Clinical Outcome

  4. 2019

    S119 THE ROLE OF RECURRENT SOMATIC ALTERATIONS IN THE NON-CODING GENOME WITH FUNCTIONAL IMPLICATIONS IN MM

    Samur M, Szalat R, Aktas Samur A, …, Munshi N

    HemaSphere3(S1):11-12DOI: S119 THE ROLE OF RECURRENT SOMATIC ALTERATIONS IN THE NON-CODING GENOME WITH FUNCTIONAL IMPLICATIONS IN MM

  5. 2018

    Chromatin Accessibility Profiling Reveals Cis-Regulatory Heterogeneity and Novel Transcription Factor Dependencies in Multiple Myeloma

    Ott CJ, Szalat R, Lawlor M, …, Munshi N

    Blood132(Supplement 1):1313-1313DOI: Chromatin Accessibility Profiling Reveals Cis-Regulatory Heterogeneity and Novel Transcription Factor Dependencies in Multiple Myeloma

  6. 2018

    Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

    Samur MK, Chakraborty C, Szalat R, …, Munshi N

    Blood132(Supplement 1):190-190DOI: Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

  7. 2017

    Integrative Oncogenomic Analysis Combining Whole Genome, Transcriptome and Epigenome Identifies Altered Chromatin Accessibility Landscape in Multiple Myeloma

    Szalat R, Samur MK, Ott CJ, Lawlor M, Epstein C, Abraham BJ, Lin CY, et al.

    Blood130:328